Predominant cortical dysfunction in Guadeloupean parkinsonism
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چکیده
منابع مشابه
Predominant cortical dysfunction in Guadeloupean parkinsonism.
Atypical parkinsonism is extremely frequent in Guadeloupe and may have an environmental cause. One-half of the patients with this tauopathy have dopa-resistant parkinsonism, tremor, subcortical dementia and abnormal eye movements suggestive of progressive supranuclear palsy (PSP). They also have hallucinations, dysautonomia, which are not characteristic of PSP. Furthermore, the oculomotor abnor...
متن کاملGuadeloupean parkinsonism: a cluster of progressive supranuclear palsy-like tauopathy.
An unusually high frequency of atypical Parkinson syndrome has been delineated over the last 5 years in the French West Indies. Postural instability with early falls, prominent frontal lobe dysfunction and pseudo-bulbar palsy were common and three-quarters of the patients were L-dopa unresponsive. One-third of all patients seen had probable progressive supranuclear palsy (PSP). This new focus o...
متن کاملMagnetic resonance imaging lesion pattern in Guadeloupean parkinsonism is distinct from progressive supranuclear palsy.
In the Caribbean island of Guadeloupe, patients with atypical parkinsonism develop a progressive supranuclear palsy-like syndrome, named Guadeloupean parkinsonism. Unlike the classical forms of progressive supranuclear palsy, they develop hallucinations and myoclonus. As lesions associated with Guadeloupean parkinsonism are poorly characterized, it is not known to what extent they differ from p...
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Parkinsonism is a syndrome with six major characteristics: Tremor at rest, rigidity, bradykinesia, loss of postural reflexes, flexed posture, and freezing. 1 Parkinson's disease (PD) is the most common form of Parkinsonism, 1 but there are many other causes (i.e., drugs), 2 clinician should be alert to alternative diagnoses, especially if patients with Parkinsonism have atypical findings for PD...
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ژورنال
عنوان ژورنال: Brain
سال: 2008
ISSN: 0006-8950,1460-2156
DOI: 10.1093/brain/awn219